[1]穆萍萍,孙钦峰.牙龈卟啉单胞菌对人类免疫缺陷病毒-1致病性的影响[J].牙体牙髓牙周病学杂志,2011,21(07):420-423.
 MU Ping-ping,SUN Qin-feng.Effects of Porphyromonas gingivalis on HIV-1 pathogenesis[J].Chinese journal of conservative dentistry,2011,21(07):420-423.
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牙龈卟啉单胞菌对人类免疫缺陷病毒-1致病性的影响
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《牙体牙髓牙周病学杂志》[ISSN:1006-6977/CN:61-1281/TN]

卷:
21
期数:
2011年07期
页码:
420-423
栏目:
综述
出版日期:
2011-07-31

文章信息/Info

Title:
Effects of Porphyromonas gingivalis on HIV-1 pathogenesis
作者:
穆萍萍 孙钦峰
山东大学口腔医学院, 山东 济南 250012
Author(s):
MU Ping-ping SUN Qin-feng
College of Stopmatology, Shandong University, Jinan 250012, China
关键词:
[关键词]HIV-1 牙龈卟啉单胞菌 牙周病
Keywords:
[Key words] HIV-1 Porphyromonas gingivalis periodontal disease
分类号:
R780.2
文献标志码:
A
摘要:
[摘要]人类免疫缺陷病毒-1(HIV-1)是以CD4+细胞缺损和功能障碍为主要表现的获得性免疫缺陷综合征(AIDS)的主要病原。AIDS与牙周病有密切的关系,HIV-1的感染被广泛认为是重型牙周病的危险因素,而近来研究发现牙周病可能是HIV-1感染宿主细胞、诱导潜伏的HIV-1复制的促进因素。牙龈卟啉单胞菌(Pg)是慢性牙周炎的主要致病菌之一,该文综述Pg对HIV-1致病性的影响。
Abstract:
[Abstract]HIV-1 is the main pathogen of AIDS, leading to damage and dysfunction of CD4+ cells. The relationship between AIDS and periodontal disease has been widely demonstrated, HIV-positive individuals are at risk for severe periodontitis. Furthermore, recent studies suggested that periodontal disease could be a risk factor for HIV infection of permissive cells and inducement of the reactivation of latent HIV- 1. Porphyromonas gingivalis is one of the main pathogens that cause chornic periodontitis . This review will summarize the effects of Porphyromonas gingivalis on the pathogenesis of HIV-1.
更新日期/Last Update: 2011-07-30